What are the other Names for this Condition? (Also known as/Synonyms). Genital Lentiginosis – Vulva; Vulvar Lentiginosis; Vulvar Melanosis. Until recently, pigmented genital macules have received . Table I. Clinical characteristics of previously reported and current cases of genital lentiginosis in men. No cytologic atypia of melanocytes was detectable. Information is insufficient at present to predict the natural history of genital lentiginosis or its relation to.

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Other possible microscopic findings include slight epidermal hyperplasia without atypia and increased dermal melanophages, which tend to be dendritic in penile lesions.

Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account. Create a free personal account to access your subscriptions, sign up for alerts, and more. Privacy Policy Terms of Use. In men, the penis, especially the glans, is most frequently involved, 3 whereas in women, the vulva, vagina, or perineum may be affected. Sign in to customize your interests Sign in to your personal account. Sign in to make a comment Sign in to your personal account.

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However, biopsy findings are invariably benign, showing mostly basilar hyperpigmentation. Genital lentiginosis is an uncommon condition of pigmented genital macules that has also been referred to as penile lentigenesatypical penile lentigenes1 vulvar melanosis2 and melanotc macules.

Irregular, Pigmented Genital Macules

The patient was reassured and will continue to be monitored for significant clinical changes. Create a personal account to register for email alerts with links to free full-text articles. Sign in to access your subscriptions Sign in to your personal account. Get free access to newly published lntiginosis.

Purchase access Subscribe now. Purchase access Subscribe to Lentignosis Learning for one year. It typically presents in the fourth decade of life as asymptomatic, large, multifocal patches of variegated pigmentation with irregular borders on genital skin. Our website uses cookies to enhance your experience.

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Irregular, Pigmented Genital Macules. | Dermatology | JAMA Dermatology | JAMA Network

Irregular, Pigmented Genital Macules. Microscopic examination revealed increased basilar hyperpigmentation and occasional dermal melanophages. Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more. Purchase access Subscribe to the journal.

Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. Create a free personal account to download free article PDFs, sign up for alerts, and more. Copyright American Medical Association. In contrast, women describe a very abrupt onset; this difference may be attributable to the greater difficulty of frequent self-examination in women. There was no significant increase in melanocyte number, and no atypical cells or inflammation was present.